110954-19-3

110954-19-3 structure

Name: 2-((2S,5S)-5-methyl-3,6-dioxopiperazin-2-yl)acetic acid
Chemical Name: Aspartyl-alanyl-diketopiperazine
CAS Number: 110954-19-3
Molecular Formula: C₇H₁₀N₂O₄
Molecular Weight: 186.17
Catalog: Research Areas Inflammation/Immunology
Create Date: 2019-06-29 17:33:20
Modify Date: 2025-08-25 08:53:36
Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy[1][2].

Name	Aspartyl-alanyl-diketopiperazine

Description	Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Bar-Or D, et al. Dipeptidyl peptidase IV activity in commercial solutions of human serum albumin. Anal Biochem. 2013 Oct 1;441(1):13-7. [2]. Shimonkevitz R, et al. A diketopiperazine fragment of human serum albumin modulates T-lymphocyte cytokine production through rap1. J Trauma. 2008 Jan;64(1):35-41.