2-((2S,5S)-5-methyl-3,6-dioxopiperazin-2-yl)acetic acid

Modify Date: 2024-01-19 12:00:41

2-((2S,5S)-5-methyl-3,6-dioxopiperazin-2-yl)acetic acid structure	Common Name	2-((2S,5S)-5-methyl-3,6-dioxopiperazin-2-yl)acetic acid
	CAS Number	110954-19-3	Molecular Weight	186.17
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇H₁₀N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2-((2S,5S)-5-methyl-3,6-dioxopiperazin-2-yl)acetic acid

Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy[1][2].

Name	Aspartyl-alanyl-diketopiperazine

Description	Aspartyl-alanyl-diketopiperazine (DA-DKP) is an immunomodulatory molecule generated by cleavage and cyclization from the N-terminus of human albumin and can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Bar-Or D, et al. Dipeptidyl peptidase IV activity in commercial solutions of human serum albumin. Anal Biochem. 2013 Oct 1;441(1):13-7. [2]. Shimonkevitz R, et al. A diketopiperazine fragment of human serum albumin modulates T-lymphocyte cytokine production through rap1. J Trauma. 2008 Jan;64(1):35-41.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. Bar-Or D, et al. Dipeptidyl peptidase IV activity in commercial solutions of human serum albumin. Anal Biochem. 2013 Oct 1;441(1):13-7.

[2]. Shimonkevitz R, et al. A diketopiperazine fragment of human serum albumin modulates T-lymphocyte cytokine production through rap1. J Trauma. 2008 Jan;64(1):35-41.