2055015-61-5
2055015-61-5 structure
- Name: GLPG2451
- Chemical Name: GLPG2451
- CAS Number: 2055015-61-5
- Molecular Formula: C16H16F3N3O5S
- Molecular Weight: 419.38
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel CFTR
- Create Date: 2019-07-01 01:26:15
- Modify Date: 2024-01-02 15:54:09
-
GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM[1].
| Name | GLPG2451 |
|---|
| Description | GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
Cystic fibrosis transmembrane conductance regulator[1] |
| In Vitro | GLPG2451 has an EC50 value of 675 nM and an efficacy level of 147% of that of VX770 in G551D/F508del cells[1]. |
| References |
| Molecular Formula | C16H16F3N3O5S |
|---|---|
| Molecular Weight | 419.38 |