GLPG2451
Modify Date: 2024-01-02 15:54:09
GLPG2451 structure
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Common Name | GLPG2451 | ||
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| CAS Number | 2055015-61-5 | Molecular Weight | 419.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H16F3N3O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GLPG2451GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM[1]. |
| Name | GLPG2451 |
|---|
| Description | GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator, which effectively potentiates low temperature rescued F508del CFTR with an EC50 of 11.1 nM[1]. |
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| Related Catalog | |
| Target |
Cystic fibrosis transmembrane conductance regulator[1] |
| In Vitro | GLPG2451 has an EC50 value of 675 nM and an efficacy level of 147% of that of VX770 in G551D/F508del cells[1]. |
| References |
| Molecular Formula | C16H16F3N3O5S |
|---|---|
| Molecular Weight | 419.38 |