1992047-64-9

1992047-64-9 structure

Name: MS 023 dihydrochloride
Chemical Name: MS023 dihydrochloride
CAS Number: 1992047-64-9
Molecular Formula: C₁₇H₂₇Cl₂N₃O
Molecular Weight: 360.32
Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
Create Date: 2019-06-29 08:40:05
Modify Date: 2024-01-14 05:44:21
MS023 is a potent, selective inhibitor of protein arginine methyltransferases (PRMTs) inhibitor, with IC50s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, respectively[1].

Name	MS023 dihydrochloride

Description	MS023 is a potent, selective inhibitor of protein arginine methyltransferases (PRMTs) inhibitor, with IC50s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
Target	IC50: 30 nM (PRMT1), 119 nM (PRMT3), 83 nM (PRMT4), 4 nM (PRMT6), 5 nM (PRMT8)[1]
References	[1]. Eram MS, et al. A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases. ACS Chem Biol. 2016 Mar 18;11(3):772-81.