MS 023 dihydrochloride

Modify Date: 2024-01-14 05:44:21

MS 023 dihydrochloride Structure
MS 023 dihydrochloride structure
Common Name MS 023 dihydrochloride
CAS Number 1992047-64-9 Molecular Weight 360.32
Density N/A Boiling Point N/A
Molecular Formula C17H27Cl2N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MS 023 dihydrochloride


MS023 is a potent, selective inhibitor of protein arginine methyltransferases (PRMTs) inhibitor, with IC50s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, respectively[1].

 Names

Name MS023 dihydrochloride

 MS 023 dihydrochloride Biological Activity

Description MS023 is a potent, selective inhibitor of protein arginine methyltransferases (PRMTs) inhibitor, with IC50s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, respectively[1].
Related Catalog
Target

IC50: 30 nM (PRMT1), 119 nM (PRMT3), 83 nM (PRMT4), 4 nM (PRMT6), 5 nM (PRMT8)[1]

References

[1]. Eram MS, et al. A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases. ACS Chem Biol. 2016 Mar 18;11(3):772-81.

 Chemical & Physical Properties

Molecular Formula C17H27Cl2N3O
Molecular Weight 360.32
Storage condition 2-8℃
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Price: ¥793/10 mM * 1 mL in DMSO

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