1240305-17-2

1240305-17-2 structure

Name: SGL5213
Chemical Name: SGL5213
CAS Number: 1240305-17-2
Molecular Formula: C₃₇H₅₅N₃O₈
Molecular Weight: 669.85
Catalog: Signaling Pathways Membrane Transporter/Ion Channel SGLT
Create Date: 2019-06-30 17:57:15
Modify Date: 2024-01-18 20:45:25
SGL5213 is a potent, oral active and low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor, with IC50 values of 29 nM and 20 nM for hSGLT1 and hSGLT2, respectively. SGL5213 has potential to treat type 2 diabetes treatment[1].

Name	SGL5213

Description	SGL5213 is a potent, oral active and low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor, with IC50 values of 29 nM and 20 nM for hSGLT1 and hSGLT2, respectively. SGL5213 has potential to treat type 2 diabetes treatment[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> SGLT
Target	IC50: 29nM/20 nM (hSGLT1/ hSGLT2)[1].
References	[1]. Kuroda S, et al. Discovery of potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor SGL5213 for type 2 diabetes treatment. Bioorg Med Chem. 2019 Jan 15;27(2):394-409.

Molecular Formula	C₃₇H₅₅N₃O₈
Molecular Weight	669.85