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1950628-94-0

1950628-94-0 structure
1950628-94-0 structure
  • Name: TGFβRI-IN-1
  • Chemical Name: TGFβRI-IN-1
  • CAS Number: 1950628-94-0
  • Molecular Formula: C20H14D3N5O2
  • Molecular Weight: 362.40
  • Catalog: Research Areas Cancer
  • Create Date: 2019-06-30 09:31:15
  • Modify Date: 2023-01-14 14:46:06
  • TGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor, with IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively[1] .

Name TGFβRI-IN-1
Description TGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor, with IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively[1] .
Related Catalog
Target

IC50: 2 nM (TGFβRI)[1].

References

[1]. Yong Zhang, et al. Discovery of 4-Azaindole Inhibitors of TGFβRI as Immuno-oncology Agents. ACS Med. Chem. Lett.20189111117-1122.

Molecular Formula C20H14D3N5O2
Molecular Weight 362.40