TGFβRI-IN-1

Modify Date: 2023-01-14 14:46:06

TGFβRI-IN-1 Structure
TGFβRI-IN-1 structure
Common Name TGFβRI-IN-1
CAS Number 1950628-94-0 Molecular Weight 362.40
Density N/A Boiling Point N/A
Molecular Formula C20H14D3N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TGFβRI-IN-1


TGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor, with IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively[1] .

 Names

Name TGFβRI-IN-1

 TGFβRI-IN-1 Biological Activity

Description TGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor, with IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively[1] .
Related Catalog
Target

IC50: 2 nM (TGFβRI)[1].

References

[1]. Yong Zhang, et al. Discovery of 4-Azaindole Inhibitors of TGFβRI as Immuno-oncology Agents. ACS Med. Chem. Lett.20189111117-1122.

 Chemical & Physical Properties

Molecular Formula C20H14D3N5O2
Molecular Weight 362.40
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