Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

1638646-27-1

1638646-27-1 structure

1638646-27-1 structure

Name: VU0453379
Chemical Name: VU0453379
CAS Number: 1638646-27-1
Molecular Formula: C₂₆H₃₄N₄O₂
Molecular Weight: 434.57
Catalog: Signaling Pathways GPCR/G Protein Glucagon Receptor
Create Date: 2019-06-29 22:10:04
Modify Date: 2024-04-01 19:13:40
VU0453379 is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R) with an EC50 of 1.3 μM[1].

Name	VU0453379

Description	VU0453379 is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R) with an EC50 of 1.3 μM[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Glucagon Receptor
Target	EC50: 1.3 μM (GLP-1R)[1]
References	[1]. Morris LC, et al. Discovery of (S)-2-cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): a novel, CNS penetrant glucagon-like peptide 1 receptor (GLP-1R) positive allosteric modulator (PAM). J Med Chem. 2014 Dec 11;57(23):10192-7.

Molecular Formula	C₂₆H₃₄N₄O₂
Molecular Weight	434.57

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.