Shanghai Nianxing Industrial Co., Ltd
China
Product Name: dBET57
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: dBET57
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: dBET57
Price: $850.0/100mg $1600.0/250mg $3200.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

1883863-52-2

1883863-52-2 structure

1883863-52-2 structure

Name: dBET57
Chemical Name: dBET57
CAS Number: 1883863-52-2
Molecular Formula: C₃₄H₃₁ClN₈O₅S
Molecular Weight: 699.18
Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
Create Date: 2019-08-04 09:55:58
Modify Date: 2025-08-26 11:01:48
dBET57 is a potent and selective heterobifunctional degrader of BRD4 based on the PROTAC technology, with a DC50/5h of 500 nM for BRD4BD1, and is inactive on BRD4BD2[1].

Name	dBET57

Description	dBET57 is a potent and selective heterobifunctional degrader of BRD4 based on the PROTAC technology, with a DC50/5h of 500 nM for BRD4BD1, and is inactive on BRD4BD2[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	DC50/5h: 500 nM (BRD4BD1)[1]
References	[1]. Nowak RP, et al. Plasticity in binding confers selectivity in ligand-induced protein degradation. Nat Chem Biol. 2018 Jul;14(7):706-714.

Molecular Formula	C₃₄H₃₁ClN₈O₅S
Molecular Weight	699.18

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.