dBET57
Modify Date: 2025-08-26 11:01:48
dBET57 structure
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Common Name | dBET57 | ||
|---|---|---|---|---|
| CAS Number | 1883863-52-2 | Molecular Weight | 699.18 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C34H31ClN8O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of dBET57dBET57 is a potent and selective heterobifunctional degrader of BRD4 based on the PROTAC technology, with a DC50/5h of 500 nM for BRD4BD1, and is inactive on BRD4BD2[1]. |
| Name | dBET57 |
|---|
| Description | dBET57 is a potent and selective heterobifunctional degrader of BRD4 based on the PROTAC technology, with a DC50/5h of 500 nM for BRD4BD1, and is inactive on BRD4BD2[1]. |
|---|---|
| Related Catalog | |
| Target |
DC50/5h: 500 nM (BRD4BD1)[1] |
| References |
| Molecular Formula | C34H31ClN8O5S |
|---|---|
| Molecular Weight | 699.18 |
| InChIKey | CZRLOIDJCMKJHE-UXMRNZNESA-N |
| SMILES | Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(CC(=O)NCCNc1cccc3c1C(=O)N(C1CCC(=O)NC1=O)C3=O)c1nnc(C)n1-2 |