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1472640-86-0

1472640-86-0 structure
1472640-86-0 structure
  • Name: KT185
  • Chemical Name: KT185
  • CAS Number: 1472640-86-0
  • Molecular Formula: C32H33N5O2
  • Molecular Weight: 519.64
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease MAGL
  • Create Date: 2019-08-03 20:42:59
  • Modify Date: 2024-01-16 19:53:26
  • KT185 is an orally-bioavailable, brain-penetrant and selective ABHD6 inhibitor, with an IC50 0.21 nM in Neuro2A cells[1].

Name KT185
Description KT185 is an orally-bioavailable, brain-penetrant and selective ABHD6 inhibitor, with an IC50 0.21 nM in Neuro2A cells[1].
Related Catalog
Target

IC50: ABHD6 (0.21 nM in Neuro2A cells)[1].

References

[1]. Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6). J Med Chem. 2013 Nov 14;56(21):8270-9.

Molecular Formula C32H33N5O2
Molecular Weight 519.64
RIDADR NONH for all modes of transport
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