KT185

Modify Date: 2024-01-16 19:53:26

KT185 Structure
KT185 structure
Common Name KT185
CAS Number 1472640-86-0 Molecular Weight 519.64
Density N/A Boiling Point N/A
Molecular Formula C32H33N5O2 Melting Point N/A
MSDS USA Flash Point N/A

 Use of KT185


KT185 is an orally-bioavailable, brain-penetrant and selective ABHD6 inhibitor, with an IC50 0.21 nM in Neuro2A cells[1].

 Names

Name KT185

 KT185 Biological Activity

Description KT185 is an orally-bioavailable, brain-penetrant and selective ABHD6 inhibitor, with an IC50 0.21 nM in Neuro2A cells[1].
Related Catalog
Target

IC50: ABHD6 (0.21 nM in Neuro2A cells)[1].

References

[1]. Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6). J Med Chem. 2013 Nov 14;56(21):8270-9.

 Chemical & Physical Properties

Molecular Formula C32H33N5O2
Molecular Weight 519.64

 Safety Information

RIDADR NONH for all modes of transport