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1062648-63-8

1062648-63-8 structure
1062648-63-8 structure
  • Name: DMT1 blocker 2
  • Chemical Name: DMT1 blocker 2
  • CAS Number: 1062648-63-8
  • Molecular Formula: C16H13N3O
  • Molecular Weight: 263.29
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2019-09-10 15:40:48
  • Modify Date: 2024-01-12 02:44:46
  • DMT1 blocker 2, Compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 of 0.83 μM, is expected to block iron uptake by enterocytes in vivo[1].

Name DMT1 blocker 2
Description DMT1 blocker 2, Compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 of 0.83 μM, is expected to block iron uptake by enterocytes in vivo[1].
Related Catalog
In Vitro IC50: 0.83 μM (DMT1 blocker 2)[1]
References

[1]. Cadieux JA, et al. Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1). Bioorg Med Chem Lett. 2012 Jan 1;22(1):90-5.

Molecular Formula C16H13N3O
Molecular Weight 263.29