DMT1 blocker 2

Modify Date: 2024-01-12 02:44:46

DMT1 blocker 2 Structure
DMT1 blocker 2 structure
Common Name DMT1 blocker 2
CAS Number 1062648-63-8 Molecular Weight 263.29
Density N/A Boiling Point N/A
Molecular Formula C16H13N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DMT1 blocker 2


DMT1 blocker 2, Compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 of 0.83 μM, is expected to block iron uptake by enterocytes in vivo[1].

 Names

Name DMT1 blocker 2

 DMT1 blocker 2 Biological Activity

Description DMT1 blocker 2, Compound 12f, is a direct inhibitor of divalent metal transporter 1 (DMT1) with an IC50 of 0.83 μM, is expected to block iron uptake by enterocytes in vivo[1].
Related Catalog
In Vitro IC50: 0.83 μM (DMT1 blocker 2)[1]
References

[1]. Cadieux JA, et al. Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1). Bioorg Med Chem Lett. 2012 Jan 1;22(1):90-5.

 Chemical & Physical Properties

Molecular Formula C16H13N3O
Molecular Weight 263.29
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