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850330-18-6

850330-18-6 structure
850330-18-6 structure
  • Name: ML 604086
  • Chemical Name: ML604086
  • CAS Number: 850330-18-6
  • Molecular Formula: C27H32N4O4S
  • Molecular Weight: 508.63
  • Catalog: Signaling Pathways GPCR/G Protein CCR
  • Create Date: 2019-10-08 12:42:52
  • Modify Date: 2024-01-02 18:13:09
  • ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations[1][2].

Name ML604086
Description ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations[1][2].
Related Catalog
Target

CCR8[1][2].

References

[1]. James E. Pease, et al. Chemokine Receptors in Allergy, Inflammation, and Infectious Disease. Top Med Chem (2015) 14: 1-40.

[2]. Lin Wang, et al. Antagonism of chemokine receptor CCR8 is ineffective in a primate model of asthma. Thorax 2013;68:506–512.

Molecular Formula C27H32N4O4S
Molecular Weight 508.63
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