ML 604086

Modify Date: 2024-01-02 18:13:09

ML 604086 Structure
ML 604086 structure
Common Name ML 604086
CAS Number 850330-18-6 Molecular Weight 508.63
Density N/A Boiling Point N/A
Molecular Formula C27H32N4O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ML 604086


ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations[1][2].

 Names

Name ML604086

 ML 604086 Biological Activity

Description ML604086 is a selective CCR8 inhibitor, inhibiting CCL1 binding to CCR8 on circulating T-cells. ML604086 inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations[1][2].
Related Catalog
Target

CCR8[1][2].

References

[1]. James E. Pease, et al. Chemokine Receptors in Allergy, Inflammation, and Infectious Disease. Top Med Chem (2015) 14: 1-40.

[2]. Lin Wang, et al. Antagonism of chemokine receptor CCR8 is ineffective in a primate model of asthma. Thorax 2013;68:506–512.

 Chemical & Physical Properties

Molecular Formula C27H32N4O4S
Molecular Weight 508.63
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