256497-58-2
256497-58-2 structure
- Name: CMLD010509
- Chemical Name: CMLD010509
- CAS Number: 256497-58-2
- Molecular Formula: C27H26BrNO7
- Molecular Weight: 556.40
- Catalog: Signaling Pathways Apoptosis Apoptosis
- Create Date: 2019-12-08 12:47:32
- Modify Date: 2024-04-01 12:06:02
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CMLD010509 (SDS-1-021) is a highly specific inhibitor of the oncogenic translation program supporting multiple myeloma (MM)-including key oncoproteins such as MYC, MDM2, CCND1, MAF, and MCL-1. CMLD010509 (SDS-1-021) shows an IC50 below 10 nM for most MM cell lines and induces apoptosis. CMLD010509 (SDS-1-021) is a potent and selective translation inhibitor through an eIF4E phosphorylation-independent mechanism[1].
| Name | CMLD010509 |
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| Description | CMLD010509 (SDS-1-021) is a highly specific inhibitor of the oncogenic translation program supporting multiple myeloma (MM)-including key oncoproteins such as MYC, MDM2, CCND1, MAF, and MCL-1. CMLD010509 (SDS-1-021) shows an IC50 below 10 nM for most MM cell lines and induces apoptosis. CMLD010509 (SDS-1-021) is a potent and selective translation inhibitor through an eIF4E phosphorylation-independent mechanism[1]. |
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| Molecular Formula | C27H26BrNO7 |
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| Molecular Weight | 556.40 |
| Hazard Codes | Xi |
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