2307461-45-4

2307461-45-4 structure

Name: FAK ligand-Linker Conjugate 1
Chemical Name: FAK ligand-Linker Conjugate 1
CAS Number: 2307461-45-4
Molecular Formula: C₂₅H₂₈F₃N₅O₆S
Molecular Weight: 583.58
Catalog: Research Areas Cancer
Create Date: 2019-12-09 10:36:19
Modify Date: 2024-01-15 06:11:36
FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation[1].

Name	FAK ligand-Linker Conjugate 1

Description	FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Cromm PM, et al. Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation. J Am Chem Soc. 2018 Dec 12;140(49):17019-17026.

Molecular Formula	C₂₅H₂₈F₃N₅O₆S
Molecular Weight	583.58