2172617-16-0
2172617-16-0 structure
- Name: YKL-06-062
- Chemical Name: YKL-06-062
- CAS Number: 2172617-16-0
- Molecular Formula: C31H39N7O
- Molecular Weight: 525.69
- Create Date: 2019-12-08 15:12:19
- Modify Date: 2025-08-25 10:13:03
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YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC50 of 2.12 nM/1.40 nM/2.86 nM, respectively. YKL-06-062 is the structural analog of YKL-06-062[1].
| Name | YKL-06-062 |
|---|
| Description | YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC50 of 2.12 nM/1.40 nM/2.86 nM, respectively. YKL-06-062 is the structural analog of YKL-06-062[1]. |
|---|---|
| In Vitro | YKL 06-062 (0.0004-16 μM; 3 hours) increases MITF mRNA expression in a dose-dependent manner[1]. RT-PCR[1] Cell Line: Human melanocyte cells, UACC62 melanoma cells Concentration: 0.0004 μM, 0.004 μM, 0.04 μM, 0.4 μM, 4 μM,8 μM,16 μM Incubation Time: 3 hours Result: Unregulated MITF mRNA expression. |
| References |
| Molecular Formula | C31H39N7O |
|---|---|
| Molecular Weight | 525.69 |