YKL-06-062

Modify Date: 2024-01-10 17:31:02

YKL-06-062 structure	Common Name	YKL-06-062
	CAS Number	2172617-16-0	Molecular Weight	525.69
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₁H₃₉N₇O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of YKL-06-062

YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC50 of 2.12 nM/1.40 nM/2.86 nM, respectively. YKL-06-062 is the structural analog of YKL-06-062[1].

Name	YKL-06-062

Description	YKL-06-062 is a second-generation salt-inducible kinase (SIK) inhibitor with an IC50 of 2.12 nM/1.40 nM/2.86 nM, respectively. YKL-06-062 is the structural analog of YKL-06-062[1].
In Vitro	YKL 06-062 (0.0004-16 μM; 3 hours) increases MITF mRNA expression in a dose-dependent manner[1]. RT-PCR[1] Cell Line: Human melanocyte cells, UACC62 melanoma cells Concentration: 0.0004 μM, 0.004 μM, 0.04 μM, 0.4 μM, 4 μM,8 μM,16 μM Incubation Time: 3 hours Result: Unregulated MITF mRNA expression.
References	[1]. Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19(11):2177-2184.

Molecular Formula	C₃₁H₃₉N₇O
Molecular Weight	525.69

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: YKL-06-062
Price: Negotiable
Purity: 99.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: YKL-06-062
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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