1648843-04-2

1648843-04-2 structure

Name: SX-682
Chemical Name: SX-682
CAS Number: 1648843-04-2
Molecular Formula: C₁₉H₁₄BF₄N₃O₄S
Molecular Weight: 467.20
Catalog: Signaling Pathways GPCR/G Protein CXCR
Create Date: 2019-12-08 17:03:19
Modify Date: 2024-01-06 16:16:32
SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity[1].

Name	SX-682
Synonyms	MFCD28502254

Description	SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> CXCR Signaling Pathways >> Immunology/Inflammation >> CXCR
Target	CXCR1 CXCR2
References	[1]. Sun L, et al. Inhibiting myeloid-derived suppressor cell trafficking enhances T cell immunotherapy. JCI Insight. 2019 Apr 4;4(7).