SX-682

Modify Date: 2024-01-06 16:16:32

SX-682 Structure
SX-682 structure
Common Name SX-682
CAS Number 1648843-04-2 Molecular Weight 467.20
Density 1.53±0.1 g/cm3(Predicted) Boiling Point N/A
Molecular Formula C19H14BF4N3O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SX-682


SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity[1].

 Names

Name SX-682
Synonym More Synonyms

 SX-682 Biological Activity

Description SX-682 is an orally bioavailable, potent allosteric inhibitor of CXCR1 and CXCR2. SX-682 can block tumor myeloid-derived suppressor cells (MDSCs) recruitment and enhance T cell activation and antitumor immunity[1].
Related Catalog
Target

CXCR1

CXCR2

References

[1]. Sun L, et al. Inhibiting myeloid-derived suppressor cell trafficking enhances T cell immunotherapy. JCI Insight. 2019 Apr 4;4(7).

 Chemical & Physical Properties

Density 1.53±0.1 g/cm3(Predicted)
Molecular Formula C19H14BF4N3O4S
Molecular Weight 467.20

 Synonyms

MFCD28502254
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