1421958-72-6
1421958-72-6 structure
- Name: M2WJ-332
- Chemical Name: N-{[5-(2-Thienyl)-1,2-oxazol-3-yl]methyl}-1-adamantanamine
- CAS Number: 1421958-72-6
- Molecular Formula: C18H22N2OS
- Molecular Weight: 314.445
- Create Date: 2020-01-12 19:18:51
- Modify Date: 2024-04-05 12:55:51
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A potent inhibitor of drug-resistant S31N mutant of the M2 ion channel of influenza A virus with IC50 of 153 nM; is more potent against S31N than amantadine against the WT M2.
| Name | N-{[5-(2-Thienyl)-1,2-oxazol-3-yl]methyl}-1-adamantanamine |
|---|---|
| Synonyms |
N-{[5-(2-Thienyl)-1,2-oxazol-3-yl]methyl}-1-adamantanamine
3-Isoxazolemethanamine, 5-(2-thienyl)-N-tricyclo[3.3.1.13,7]dec-1-yl- |
| Description | A potent inhibitor of drug-resistant S31N mutant of the M2 ion channel of influenza A virus with IC50 of 153 nM; is more potent against S31N than amantadine against the WT M2. |
|---|---|
| References | References 1. Wang J, et al. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1315-20. View Related Products by Target Influenza Virus |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 465.9±35.0 °C at 760 mmHg |
| Molecular Formula | C18H22N2OS |
| Molecular Weight | 314.445 |
| Flash Point | 235.6±25.9 °C |
| Exact Mass | 314.145294 |
| LogP | 4.42 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.629 |