1425049-20-2
1425049-20-2 structure
- Name: RB-005
- Chemical Name: 1-[2-(4-Octylphenyl)ethyl]-4-piperidinol
- CAS Number: 1425049-20-2
- Molecular Formula: C21H35NO
- Molecular Weight: 317.509
- Create Date: 2020-01-20 19:11:56
- Modify Date: 2024-01-08 17:56:48
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RB-005 (RB-005) is a potent, selective inhibitor of sphingosine kinase SphK1 (SK1) with IC50 of 3.6 uM, displays 15-fold selectivity over SphK2.
| Name | 1-[2-(4-Octylphenyl)ethyl]-4-piperidinol |
|---|---|
| Synonyms |
1-[2-(4-Octylphenyl)ethyl]-4-piperidinol
4-Piperidinol, 1-[2-(4-octylphenyl)ethyl]- |
| Description | RB-005 (RB-005) is a potent, selective inhibitor of sphingosine kinase SphK1 (SK1) with IC50 of 3.6 uM, displays 15-fold selectivity over SphK2. |
|---|---|
| References | References 1. Baek DJ, et al. Chem Commun (Camb). 2013 Mar 14;49(21):2136-8. 2. Baek DJ, et al. J Med Chem. 2013 Nov 27;56(22):9310-27. 3. MacRitchie N, et al. Cell Signal. 2016 Aug;28(8):946-55. View Related Products by Target Sphingosine kinase (SphK) |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 452.0±30.0 °C at 760 mmHg |
| Molecular Formula | C21H35NO |
| Molecular Weight | 317.509 |
| Flash Point | 35.6±18.7 °C |
| Exact Mass | 317.271851 |
| LogP | 5.61 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.524 |