RB-005

Modify Date: 2024-01-08 17:56:48

RB-005 Structure
RB-005 structure
Common Name RB-005
CAS Number 1425049-20-2 Molecular Weight 317.509
Density 1.0±0.1 g/cm3 Boiling Point 452.0±30.0 °C at 760 mmHg
Molecular Formula C21H35NO Melting Point N/A
MSDS N/A Flash Point 35.6±18.7 °C

 Use of RB-005


RB-005 (RB-005) is a potent, selective inhibitor of sphingosine kinase SphK1 (SK1) with IC50 of 3.6 uM, displays 15-fold selectivity over SphK2.

 Names

Name 1-[2-(4-Octylphenyl)ethyl]-4-piperidinol
Synonym More Synonyms

 RB-005 Biological Activity

Description RB-005 (RB-005) is a potent, selective inhibitor of sphingosine kinase SphK1 (SK1) with IC50 of 3.6 uM, displays 15-fold selectivity over SphK2.
References References 1. Baek DJ, et al. Chem Commun (Camb). 2013 Mar 14;49(21):2136-8. 2. Baek DJ, et al. J Med Chem. 2013 Nov 27;56(22):9310-27. 3. MacRitchie N, et al. Cell Signal. 2016 Aug;28(8):946-55. View Related Products by Target Sphingosine kinase (SphK)

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 452.0±30.0 °C at 760 mmHg
Molecular Formula C21H35NO
Molecular Weight 317.509
Flash Point 35.6±18.7 °C
Exact Mass 317.271851
LogP 5.61
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.524

 Synonyms

1-[2-(4-Octylphenyl)ethyl]-4-piperidinol
4-Piperidinol, 1-[2-(4-octylphenyl)ethyl]-