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  • DC Chemicals Limited
  • China
  • Product Name: EML-631
  • Price: $Inquiry/25mg $Inquiry/100mg $Inquiry/250mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

2101206-36-2

2101206-36-2 structure
2101206-36-2 structure
  • Name: EML-631
  • Chemical Name: (2-{[4-(1-Pyrrolidinylmethoxy)phenyl]amino}-1,4-phenylene)bis({4-[2-(1-pyrrolidinyl)ethyl]-1-piperidinyl}methanone)
  • CAS Number: 2101206-36-2
  • Molecular Formula: C41H60N6O3
  • Molecular Weight: 684.953
  • Create Date: 2020-01-20 17:06:56
  • Modify Date: 2024-01-19 10:36:11
  • A small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 4 uM; shows increased selectivity and engages SPIN1 in cells, block its ability to 'read' H3K4me3 marks and inhibit its transcriptional-coactivator activity.

Name (2-{[4-(1-Pyrrolidinylmethoxy)phenyl]amino}-1,4-phenylene)bis({4-[2-(1-pyrrolidinyl)ethyl]-1-piperidinyl}methanone)
Synonyms (2-{[4-(1-Pyrrolidinylmethoxy)phenyl]amino}-1,4-phenylene)bis({4-[2-(1-pyrrolidinyl)ethyl]-1-piperidinyl}methanone)
Methanone, 1,1'-[2-[[4-(1-pyrrolidinylmethoxy)phenyl]amino]-1,4-phenylene]bis[1-[4-[2-(1-pyrrolidinyl)ethyl]-1-piperidinyl]-
Description A small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 4 uM; shows increased selectivity and engages SPIN1 in cells, block its ability to 'read' H3K4me3 marks and inhibit its transcriptional-coactivator activity.
References References 1. Bae N, et al. Nat Chem Biol. 2017 May 15. doi: 10.1038/nchembio.2377. 2. Wang W, et al. EMBO Rep. 2011 Oct 28;12(11):1160-6. View Related Products by Target Other Targets
Density 1.2±0.1 g/cm3
Boiling Point 821.3±65.0 °C at 760 mmHg
Molecular Formula C41H60N6O3
Molecular Weight 684.953
Flash Point 450.5±34.3 °C
Exact Mass 684.472717
LogP 4.49
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.594