2101954-85-0
2101954-85-0 structure
- Name: EML-633
- Chemical Name: EML-633
- CAS Number: 2101954-85-0
- Molecular Formula: C42H62N6O2
- Molecular Weight: 682.998
- Create Date: 2020-01-20 10:09:56
- Modify Date: 2023-01-14 17:06:44
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A small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 2 uM; shows increased selectivity and engages SPIN1 in cells, block its ability to 'read' H3K4me3 marks and inhibit its transcriptional-coactivator activity.
| Name | EML-633 |
|---|
| Description | A small-molecule inhibitor of Spindlin1 (SPIN1) with Kd of 2 uM; shows increased selectivity and engages SPIN1 in cells, block its ability to 'read' H3K4me3 marks and inhibit its transcriptional-coactivator activity. |
|---|---|
| References | References 1. Bae N, et al. Nat Chem Biol. 2017 May 15. doi: 10.1038/nchembio.2377. 2. Wang W, et al. EMBO Rep. 2011 Oct 28;12(11):1160-6. View Related Products by Target Other Targets |
| Molecular Formula | C42H62N6O2 |
|---|---|
| Molecular Weight | 682.998 |