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1448189-98-7

1448189-98-7 structure
1448189-98-7 structure
  • Name: VHL Ligand 3
  • Chemical Name: 3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide
  • CAS Number: 1448189-98-7
  • Molecular Formula: C27H38N4O5S
  • Molecular Weight: 530.679
  • Catalog: Signaling Pathways PROTAC Ligand for E3 Ligase
  • Create Date: 2020-01-11 16:34:59
  • Modify Date: 2024-01-13 12:48:41
  • A VHL ligand for PROTAC.

Name 3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide
Synonyms L-Prolinamide, N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide
Description A VHL ligand for PROTAC.
References References 1. Wurz RP, et al. J Med Chem. 2017 Apr 17. doi: 10.1021/acs.jmedchem.6b01781. 2. Zengerle M, et al. ACS Chem Biol. 2015 Aug 21;10(8):1770-7. View Related Products by Target E3 Ligase Ligand
Density 1.2±0.1 g/cm3
Boiling Point 755.7±60.0 °C at 760 mmHg
Molecular Formula C27H38N4O5S
Molecular Weight 530.679
Flash Point 410.9±32.9 °C
Exact Mass 530.256287
LogP 2.63
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.572
Hazard Codes Xi