VHL Ligand 3
Modify Date: 2024-01-13 12:48:41
VHL Ligand 3 structure
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Common Name | VHL Ligand 3 | ||
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| CAS Number | 1448189-98-7 | Molecular Weight | 530.679 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 755.7±60.0 °C at 760 mmHg | |
| Molecular Formula | C27H38N4O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 410.9±32.9 °C | |
Use of VHL Ligand 3A VHL ligand for PROTAC. |
| Name | 3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide |
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| Synonym | More Synonyms |
| Description | A VHL ligand for PROTAC. |
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| References | References 1. Wurz RP, et al. J Med Chem. 2017 Apr 17. doi: 10.1021/acs.jmedchem.6b01781. 2. Zengerle M, et al. ACS Chem Biol. 2015 Aug 21;10(8):1770-7. View Related Products by Target E3 Ligase Ligand |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 755.7±60.0 °C at 760 mmHg |
| Molecular Formula | C27H38N4O5S |
| Molecular Weight | 530.679 |
| Flash Point | 410.9±32.9 °C |
| Exact Mass | 530.256287 |
| LogP | 2.63 |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.572 |
| Hazard Codes | Xi |
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| L-Prolinamide, N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- |
| 3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-hydroxy-N-[4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide |