247079-84-1
247079-84-1 structure
- Name: Iperoxo
- Chemical Name: 4-(4,5-Dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethyl-2-butyn-1-aminium iodide
- CAS Number: 247079-84-1
- Molecular Formula: C10H17IN2O2
- Molecular Weight: 324.159
- Create Date: 2020-01-11 17:57:01
- Modify Date: 2024-01-10 19:19:17
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An extremely potent muscarinic receptor agonist with EC50 of 2.12 nM and 8.47 nM for M2 and M4, respectively; significantly exceeds ACh in Gi /Gs signalling competence CHO-hM2 cells.
| Name | 4-(4,5-Dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethyl-2-butyn-1-aminium iodide |
|---|---|
| Synonyms |
4-(4,5-Dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethyl-2-butyn-1-aminium iodide
2-Butyn-1-aminium, 4-[(4,5-dihydro-3-isoxazolyl)oxy]-N,N,N-trimethyl-, iodide (1:1) MFCD26793886 |
| Description | An extremely potent muscarinic receptor agonist with EC50 of 2.12 nM and 8.47 nM for M2 and M4, respectively; significantly exceeds ACh in Gi /Gs signalling competence CHO-hM2 cells. |
|---|---|
| References | References 1. Schrage R, et al. Br J Pharmacol. 2013 May;169(2):357-70. 2. Kruse AC, et al. Nature. 2013 Dec 5;504(7478):101-6. 3. Croy CH, et al. Mol Pharmacol. 2014 Jul;86(1):106-15. View Related Products by Target mAChR |
| Melting Point | 211.5 - 212.5 °C |
|---|---|
| Molecular Formula | C10H17IN2O2 |
| Molecular Weight | 324.159 |
| Exact Mass | 324.033478 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| RIDADR | NONH for all modes of transport |