142872-84-2
142872-84-2 structure
- Name: RX 871024
- Chemical Name: RX 871024
- CAS Number: 142872-84-2
- Molecular Formula: C17H15N3·HCl
- Molecular Weight: 297.78
- Create Date: 2020-01-20 09:00:56
- Modify Date: 2023-02-01 19:03:09
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A imidazoline compound that stimulate insulin release by inhibition of ATP-dependent K+ channels and inducing of Ca2+ mobilization in mouse pancreatic beta-cells; blocks ATP-dependent K+ channels and membrane depolarization, and activates voltage-dependent Ca2+ channels. Diabetes Discontinued
| Name | RX 871024 |
|---|
| Description | A imidazoline compound that stimulate insulin release by inhibition of ATP-dependent K+ channels and inducing of Ca2+ mobilization in mouse pancreatic beta-cells; blocks ATP-dependent K+ channels and membrane depolarization, and activates voltage-dependent Ca2+ channels. Diabetes Discontinued |
|---|---|
| References | References 1. Efanova IB, et al. Diabetes. 1998 Feb;47(2):211-8. 2. Zaitsev SV, et al. Diabetes. 1996 Nov;45(11):1610-8. 3. Mourtada M, et al. Eur J Pharmacol. 1998 Jun 5;350(2-3):251-8. 4. Mourtada M, et al. Br J Pharmacol. 1999 Jul;127(5):1279-87. View Related Products by Target Potassium Channel Diabetes |
| Molecular Formula | C17H15N3·HCl |
|---|---|
| Molecular Weight | 297.78 |
| RIDADR | NONH for all modes of transport |
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