956128-08-8
956128-08-8 structure
- Name: TDI-2760
- Chemical Name: TDI-2760
- CAS Number: 956128-08-8
- Molecular Formula: C18H18N4O
- Molecular Weight: 306.369
- Create Date: 2020-01-11 18:04:51
- Modify Date: 2024-03-09 21:00:05
-
TDI-2760 si a small molecule Aβ-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Aβ-fibrinogen interaction (IC50=1.67 uM) but also retains potency toward the Aβ42 aggregation inhibition process; restores the Aβ42-induced decrease in fibrin clot turbidity without affecting normal clotting in an in vitro clotting assay, effectively inhibits Aβ42 fibrillization and modulates Aβ42-induced contact system activation.
| Name | TDI-2760 |
|---|
| Description | TDI-2760 si a small molecule Aβ-aggregation inhibitor that not only shows a strong inhibitory efficacy toward the Aβ-fibrinogen interaction (IC50=1.67 uM) but also retains potency toward the Aβ42 aggregation inhibition process; restores the Aβ42-induced decrease in fibrin clot turbidity without affecting normal clotting in an in vitro clotting assay, effectively inhibits Aβ42 fibrillization and modulates Aβ42-induced contact system activation. |
|---|---|
| References | References 1. Singh PK, et al. Biochemistry. 2018 Feb 27;57(8):1399-1409. View Related Products by Target Amyloids |
| Molecular Formula | C18H18N4O |
|---|---|
| Molecular Weight | 306.369 |