1221964-37-9
1221964-37-9 structure
- Name: PS 423
- Chemical Name: PS 423
- CAS Number: 1221964-37-9
- Molecular Formula: C25H23F3O9
- Molecular Weight: 524.445
- Create Date: 2020-01-11 17:58:50
- Modify Date: 2024-01-19 13:58:26
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PS 423 is a substrate-selective inhibitor of PDK1, inhibits the phosphorylation and activation of S6K without affecting the PKB/Akt signaling pathway in HEK293 cells, the prodrug of PS210; inhibits glucose uptake in C2C12 myoblasts; inhibits S6K but not PKB/Akt downstream signaling in muscle cells.
| Name | PS 423 |
|---|
| Description | PS 423 is a substrate-selective inhibitor of PDK1, inhibits the phosphorylation and activation of S6K without affecting the PKB/Akt signaling pathway in HEK293 cells, the prodrug of PS210; inhibits glucose uptake in C2C12 myoblasts; inhibits S6K but not PKB/Akt downstream signaling in muscle cells. |
|---|---|
| References | References 1. Busschots K, et al. Chem Biol. 2012 Sep 21;19(9):1152-63. 2. Arkin MR, et al. Chem Biol. 2014 Sep 18;21(9):1102-14. View Related Products by Target PDK1 |
| Molecular Formula | C25H23F3O9 |
|---|---|
| Molecular Weight | 524.445 |