1256921-89-7
1256921-89-7 structure
- Name: KNT-127
- Chemical Name: KNT-127
- CAS Number: 1256921-89-7
- Molecular Formula: C24H24N2O2
- Molecular Weight: 372.468
- Create Date: 2020-01-11 18:43:49
- Modify Date: 2024-01-07 12:59:01
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A potent, selectove δ-opioid receptor agonist with Ki of 0.16 nM, dispalys 133.5-fold and 960.5-fold selectivity over μOR and κOR respectively; significantly decreases the duration of immobility and increased the duration of swimming without influencing spontaneous locomotor activity in mice (1mg/kg, s.c.).
| Name | KNT-127 |
|---|
| Description | A potent, selectove δ-opioid receptor agonist with Ki of 0.16 nM, dispalys 133.5-fold and 960.5-fold selectivity over μOR and κOR respectively; significantly decreases the duration of immobility and increased the duration of swimming without influencing spontaneous locomotor activity in mice (1mg/kg, s.c.). |
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| References | References 1. Nagase H, et al. Bioorg Med Chem Lett. 2010 Nov 1;20(21):6302-5. 2. Saitoh A, et al. Behav Brain Res. 2011 Oct 1;223(2):271-9. 3. Tanahashi S, et al. Neuropharmacology. 2012 Apr;62(5-6):2057-67. View Related Products by Target Opioid Receptor |
| Molecular Formula | C24H24N2O2 |
|---|---|
| Molecular Weight | 372.468 |