1262131-60-1
1262131-60-1 structure
- Name: JTZ-951 hydrochloride
- Chemical Name: JTZ-951 hydrochloride
- CAS Number: 1262131-60-1
- Molecular Formula: C17H17ClN4O4
- Molecular Weight: 376.797
- Catalog: Signaling Pathways Metabolic Enzyme/Protease HIF/HIF Prolyl-Hydroxylase
- Create Date: 2020-01-19 20:09:57
- Modify Date: 2024-04-08 18:04:34
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A novel potent, orally active HIF prolyl hydroxylase (PHD) inhibitor with IC50 of 0.22 uM for PHD2; increases EPO release from Hep3B cells with EC50 of 5.7 uM, increases hemoglobin levels in rats. Anemia Phase 2 Clinical
| Name | JTZ-951 hydrochloride |
|---|
| Description | A novel potent, orally active HIF prolyl hydroxylase (PHD) inhibitor with IC50 of 0.22 uM for PHD2; increases EPO release from Hep3B cells with EC50 of 5.7 uM, increases hemoglobin levels in rats. Anemia Phase 2 Clinical |
|---|---|
| References | References 1. Yosuke Ogoshi, et al. ACS Med. Chem. Lett., 2017, 8 (12), pp 1320-1325. View Related Products by Target HIF/HIF Prolyl-hydroxylase Anemia |
| Molecular Formula | C17H17ClN4O4 |
|---|---|
| Molecular Weight | 376.797 |