1266240-87-2
1266240-87-2 structure
- Name: IKK2-IN-8
- Chemical Name: IKK2-IN-8
- CAS Number: 1266240-87-2
- Molecular Formula: C19H20N6OS
- Molecular Weight: 380.47
- Create Date: 2020-01-12 11:28:50
- Modify Date: 2024-07-31 20:41:54
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IKK2-IN-8 is a potent, selective IKK2 inhibitor with IC50 of 6 nM, displays >40-fold selectivity over IKK1 (IC50=230 nM); inhibits lipopolysaccharide (LPS) induced TNFα production in human PBMCs with IC50 of 80 nM.
| Name | IKK2-IN-8 |
|---|
| Description | IKK2-IN-8 is a potent, selective IKK2 inhibitor with IC50 of 6 nM, displays >40-fold selectivity over IKK1 (IC50=230 nM); inhibits lipopolysaccharide (LPS) induced TNFα production in human PBMCs with IC50 of 80 nM. |
|---|---|
| References | References 1. Dyckman AJ, et al. Bioorg Med Chem Lett. 2011 Jan 1;21(1):383-6. View Related Products by Target IκB kinase (IKK) |
| Molecular Formula | C19H20N6OS |
|---|---|
| Molecular Weight | 380.47 |