1405126-60-4
1405126-60-4 structure
- Name: Pim-IN-22m
- Chemical Name: Pim-IN-22m
- CAS Number: 1405126-60-4
- Molecular Formula: C23H23F2N7
- Molecular Weight: 435.483
- Create Date: 2020-01-20 13:02:56
- Modify Date: 2024-01-16 23:10:22
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Pim-IN-22m is a potent, selective Pim1/Pim2 inhibitor with IC50 of 24/95 pM respectively; potently inhibits the phosphorylation of BAD (s112) in a cell line that expresses high levels of all Pim isoforms, KMS-12-BM (IC50=28 nM).
| Name | Pim-IN-22m |
|---|
| Description | Pim-IN-22m is a potent, selective Pim1/Pim2 inhibitor with IC50 of 24/95 pM respectively; potently inhibits the phosphorylation of BAD (s112) in a cell line that expresses high levels of all Pim isoforms, KMS-12-BM (IC50=28 nM). |
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| References | References 1. Wurz RP, et al. Bioorg Med Chem Lett. 2016 Nov 15;26(22):5580-5590. View Related Products by Target Pim |
| Molecular Formula | C23H23F2N7 |
|---|---|
| Molecular Weight | 435.483 |