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1173715-42-8

1173715-42-8 structure
1173715-42-8 structure
  • Name: hDHODH-IN-1
  • Chemical Name: hDHODH-IN-1
  • CAS Number: 1173715-42-8
  • Molecular Formula: C17H14N2O2
  • Molecular Weight: 278.31
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
  • Create Date: 2020-04-09 12:04:16
  • Modify Date: 2025-08-30 10:58:44
  • hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory effect[1].

Name hDHODH-IN-1
Description hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory effect[1].
Related Catalog
In Vitro Human dihydroorotate dehydrogenase (hDHODH) is a class-2 dihydroorotate dehydrogenase. Because DHODH is required to ensure proliferating-cell viability, inhibitors have been developed to eliminate human DHODH (hDHODH) activity, which is associated with cancers, multiple sclerosis, and autoimmune and inflammatory diseases[1].
References

[1]. Shih KC, et al. Development of a human dihydroorotate dehydrogenase (hDHODH) pharma-similarity index approach with scaffold-hopping strategy for the design of novel potential inhibitors. PLoS One. 2014 Feb 4;9(2):e87960.

Molecular Formula C17H14N2O2
Molecular Weight 278.31
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