1604821-43-3
1604821-43-3 structure
- Name: ML 278
- Chemical Name: ML 278
- CAS Number: 1604821-43-3
- Molecular Formula: C23H23N3O5S
- Molecular Weight: 453.513
- Create Date: 2020-01-11 23:05:50
- Modify Date: 2024-02-05 01:05:57
-
ML278 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 6 nM; a plasma-stable, noncytotoxic probe that exhibits moderate metabolic stability, thus displaying improved properties for in vitro and in vivo studies; increases the binding of HDL to SR-BI.
| Name | ML 278 |
|---|
| Description | ML278 is a potent and reversible inhibitor of lipid uptake via SR-BI (scavenger receptor BI) with IC50 of 6 nM; a plasma-stable, noncytotoxic probe that exhibits moderate metabolic stability, thus displaying improved properties for in vitro and in vivo studies; increases the binding of HDL to SR-BI. |
|---|---|
| References | References 1. Dockendorff C, et al. ACS Med Chem Lett. 2015 Feb 2;6(4):375-380. View Related Products by Target Scavenger Receptor |
| Molecular Formula | C23H23N3O5S |
|---|---|
| Molecular Weight | 453.513 |