1617518-22-5
1617518-22-5 structure
- Name: HJC0416
- Chemical Name: HJC0416
- CAS Number: 1617518-22-5
- Molecular Formula: C18H17ClN2O4S
- Molecular Weight: 392.854
- Create Date: 2020-01-11 16:28:50
- Modify Date: 2024-02-27 17:55:02
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A orally bioavailable small-molecule STAT3 inhibitor; inhibits the proliferation of both ER-positive, and ER-negative (triple negative) breast cancer cells with IC50 values of 1.76 uM and 1.97 uM, respectively; inhibits cell cycle progression and promotes apoptosis both in vitro and in vivo.
| Name | HJC0416 |
|---|
| Description | A orally bioavailable small-molecule STAT3 inhibitor; inhibits the proliferation of both ER-positive, and ER-negative (triple negative) breast cancer cells with IC50 values of 1.76 uM and 1.97 uM, respectively; inhibits cell cycle progression and promotes apoptosis both in vitro and in vivo. |
|---|---|
| References | References 1. Chen H, et al. Eur J Med Chem. 2014 Jul 23;82:195-203. View Related Products by Target STAT |
| Molecular Formula | C18H17ClN2O4S |
|---|---|
| Molecular Weight | 392.854 |