HJC0416

Modify Date: 2024-02-27 17:55:02

HJC0416 Structure
HJC0416 structure
Common Name HJC0416
CAS Number 1617518-22-5 Molecular Weight 392.854
Density N/A Boiling Point N/A
Molecular Formula C18H17ClN2O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HJC0416


A orally bioavailable small-molecule STAT3 inhibitor; inhibits the proliferation of both ER-positive, and ER-negative (triple negative) breast cancer cells with IC50 values of 1.76 uM and 1.97 uM, respectively; inhibits cell cycle progression and promotes apoptosis both in vitro and in vivo.

 Names

Name HJC0416

 HJC0416 Biological Activity

Description A orally bioavailable small-molecule STAT3 inhibitor; inhibits the proliferation of both ER-positive, and ER-negative (triple negative) breast cancer cells with IC50 values of 1.76 uM and 1.97 uM, respectively; inhibits cell cycle progression and promotes apoptosis both in vitro and in vivo.
References References 1. Chen H, et al. Eur J Med Chem. 2014 Jul 23;82:195-203. View Related Products by Target STAT

 Chemical & Physical Properties

Molecular Formula C18H17ClN2O4S
Molecular Weight 392.854
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