2041789-49-3
2041789-49-3 structure
- Name: PLK1-IN-14f
- Chemical Name: PLK1-IN-14f
- CAS Number: 2041789-49-3
- Molecular Formula: C19H23NO6S
- Molecular Weight: 393.454
- Create Date: 2020-01-11 18:13:49
- Modify Date: 2024-04-05 11:06:26
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PLK1-IN-14f is a potent PLK1 inhibitor, exhibits potent activity against a panel cancer cell lines with GI50 values ranging from 0.30 to 0.60 uM; causes cell-cycle arrest at the G2/M phase and induced apoptosis by targeting CDC25C and Mcl-1 proteins in A2780 ovarian cells.
| Name | PLK1-IN-14f |
|---|
| Description | PLK1-IN-14f is a potent PLK1 inhibitor, exhibits potent activity against a panel cancer cell lines with GI50 values ranging from 0.30 to 0.60 uM; causes cell-cycle arrest at the G2/M phase and induced apoptosis by targeting CDC25C and Mcl-1 proteins in A2780 ovarian cells. |
|---|---|
| References | References 1. Long Y, et al. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5674-5678. View Related Products by Target Polo-like Kinase (PLK) |
| Molecular Formula | C19H23NO6S |
|---|---|
| Molecular Weight | 393.454 |