Name | RN-9893 hydrochloride |
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Description | A potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively; >15-fold selectivity for TRPV4 over TRPV1, TRPV3 and TRPM8, and a panel of 54 other common biological targets. |
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References | References 1. Wei ZL, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5. View Related Products by Target TRP Channel |
Molecular Formula | C21H23F3N4O5S.HCl |
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Molecular Weight | 536.95 |