2109450-40-8
2109450-40-8 structure
- Name: RN 9893 hydrochloride
- Chemical Name: RN-9893 hydrochloride
- CAS Number: 2109450-40-8
- Molecular Formula: C21H23F3N4O5S.HCl
- Molecular Weight: 536.95
- Create Date: 2020-01-20 19:04:56
- Modify Date: 2025-08-25 16:16:53
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A potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively; >15-fold selectivity for TRPV4 over TRPV1, TRPV3 and TRPM8, and a panel of 54 other common biological targets.
| Name | RN-9893 hydrochloride |
|---|
| Description | A potent, selective orally-bioavailable TRPV4 antagonist with IC50 of 320, 420 and 660 nM for mouse, human and rat TRPV4 channels, respectively; >15-fold selectivity for TRPV4 over TRPV1, TRPV3 and TRPM8, and a panel of 54 other common biological targets. |
|---|---|
| References | References 1. Wei ZL, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):4011-5. View Related Products by Target TRP Channel |
| Molecular Formula | C21H23F3N4O5S.HCl |
|---|---|
| Molecular Weight | 536.95 |