276704-21-3
276704-21-3 structure
- Name: MRL-1237
- Chemical Name: MRL-1237
- CAS Number: 276704-21-3
- Molecular Formula: C19H16ClFN4
- Molecular Weight: 354.813
- Create Date: 2020-01-19 21:35:56
- Modify Date: 2024-02-10 01:13:05
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MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein; inhibits poliovirus-specific RNA synthesis in HeLa cells infected with a wild strain but not with an F164Y mutant.
| Name | MRL-1237 |
|---|
| Description | MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein; inhibits poliovirus-specific RNA synthesis in HeLa cells infected with a wild strain but not with an F164Y mutant. |
|---|---|
| References | References 1. Shimizu H, et al. J Virol. 2000 May;74(9):4146-54. 2. De Palma AM, et al. J Virol. 2008 May;82(10):4720-30. View Related Products by Target Enterovirus |
| Molecular Formula | C19H16ClFN4 |
|---|---|
| Molecular Weight | 354.813 |