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1422053-03-9

1422053-03-9 structure
1422053-03-9 structure
  • Name: TMP780
  • Chemical Name: TMP780
  • CAS Number: 1422053-03-9
  • Molecular Formula: C31H30N2O4
  • Molecular Weight: 494.58
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease ROR
  • Create Date: 2020-01-23 19:13:51
  • Modify Date: 2024-01-19 23:04:09
  • TMP780 is an inverse agonist of RORγt with an IC50 of 13 nM. RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders[1].

Name TMP780
Description TMP780 is an inverse agonist of RORγt with an IC50 of 13 nM. RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders[1].
Related Catalog
Target

IC50: 13 nM (RORγt)[1]

References

[1]. Skepner J, et al. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo. J Immunol. 2014 Mar 15;192(6):2564-75.

Molecular Formula C31H30N2O4
Molecular Weight 494.58
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