1919045-02-5

1919045-02-5 structure

Name: Aminooxy-PEG5-azide
Chemical Name: Aminooxy-PEG5-azide
CAS Number: 1919045-02-5
Molecular Formula: C₁₂H₂₆N₄O₆
Molecular Weight: 322.36
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-04-12 14:15:14
Modify Date: 2024-01-14 17:27:25
Aminooxy-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name	Aminooxy-PEG5-azide

Description	Aminooxy-PEG5-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.