Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SMS1-IN-1
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
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DC Chemicals Limited
China
Product Name: SMS1-IN-1
Price: $600.0/100mg $1100.0/250mg $2200.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: SMS1-IN-1
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

1807943-38-9

1807943-38-9 structure

1807943-38-9 structure

Name: SMS1-IN-1
Chemical Name: SMS1-IN-1
CAS Number: 1807943-38-9
Molecular Formula: C₂₃H₂₃BrN₂O₄S
Molecular Weight: 503.41
Catalog: Research Areas Inflammation/Immunology
Create Date: 2020-04-10 17:39:03
Modify Date: 2024-01-14 17:46:00
SMS1-IN-1, compound SAPA 1j, is a novel and the most potent sphingomyelin synthase 1 (SMS1) inhibitor with an IC50 value of 2.1 μM. SMS1-IN-1 has the potential for the treatment of atherosclerosis[1].

Name	SMS1-IN-1

Description	SMS1-IN-1, compound SAPA 1j, is a novel and the most potent sphingomyelin synthase 1 (SMS1) inhibitor with an IC50 value of 2.1 μM. SMS1-IN-1 has the potential for the treatment of atherosclerosis[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	IC50: 2.1 μM (SMS1)[1]
In Vitro	SMS1-IN-1 (2.5, 10 and 50 μM) has a dose-dependent inhibitory effect against SMS1, and is against SMS1 with an IC50 value of 2.1 μM[1].
References	[1]. Li YL, et al. Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors.Bioorg Med Chem. 2015 Sep 15;23(18):6173-84.

Molecular Formula	C₂₃H₂₃BrN₂O₄S
Molecular Weight	503.41

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