2093388-52-2

2093388-52-2 structure

Name: Thalidomide-NH-C4-NH-Boc
Chemical Name: Thalidomide-NH-C4-NH-Boc
CAS Number: 2093388-52-2
Molecular Formula: C₂₂H₂₈N₄O₆
Molecular Weight: 444.48
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2020-04-11 09:35:25
Modify Date: 2024-01-15 10:24:18
Thalidomide-NH-C4-NH-Boc (compound 15) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

Name	Thalidomide-NH-C4-NH-Boc

Description	Thalidomide-NH-C4-NH-Boc (compound 15) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon
References	[1]. Jiang F, et al.Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potencies.Bioorg Med Chem. 2020 Jan 1;28(1):115181.

Molecular Formula	C₂₂H₂₈N₄O₆
Molecular Weight	444.48

Hazard Codes	Xi